Betekenis van:
gene expression

gene expression
Zelfstandig naamwoord
    • conversion of the information encoded in a gene first into messenger RNA and then to a protein

    Hyperoniemen


    Voorbeeldzinnen

    1. pharmacokinetic studies of the medicinal product and the gene expression moieties (e.g. expressed proteins or genomic signatures).
    2. an nptII-type kanamycin resistance gene originating from Tn5, under the regulation of a nopaline-synthase promoter for expression in plant tissue and terminated by a polyadenylation sequence from the Agrobacterium tumefaciens nopaline-synthase gene;
    3. This is due to the extremely low probability of gene transfer from plants to bacteria and its subsequent expression and to the fact that this antibiotic resistant gene in bacteria is already widespread in the environment.
    4. The focus will be on new technologies for: sequencing; gene expression, genotyping and phenotyping; structural and functional genomics; bio-informatics and systems biology; other ‘omics’.
    5. Human pharmacodynamic studies shall address the expression and function of the nucleic acid sequence following administration of the gene therapy medicinal product.
    6. On 13 April 2007, taking into account this statement, EFSA indicated that the therapeutic effect of the antibiotics at stake will not be compromised by the presence of the nptII gene in GM plants. This is due to the extremely low probability of gene transfer from plants to bacteria and its subsequent expression and to the fact that this antibiotic resistant gene in bacteria is already widespread in the environment.